We mine fungal genome data for drugs.

Hexagon Bio is a data-driven biotech based in the Bay Area. We mine massive amounts of genomic data from fungal genomes to identify novel drugs for diseases with unmet needs. Our expertise is in genomics, synthetic biology, chemistry and computation.

The Team

Maureen Hillenmeyer, PhD Maureen is a founder and CEO of Hexagon. Previously, Maureen was director of the Genomes to Natural Products program and group leader at the Stanford Technology Genome Center. Brian Naughton, PhD Brian is a founder and head of data at Hexagon. Previously, he was founding scientist at 23andMe. Colin Harvey, PhD Colin is a founder and head of Chemistry and Biology at Hexagon. Previously, Colin led synthetic biology efforts for natural product discovery at the Stanford Genome Technology Center. Professor Yi Tang, PhD Yi is a founder of Hexagon, Professor at UCLA, and a world expert on fungal enzymes and natural products.

We are hiring!

Currently, we are hiring computational biologists, biologists with experience in automation, chemists, and more. If you are interested, email us at jobs@hexagonbio.com.

At Hexagon Bio, our mission is to discover and develop the next generation of drugs. We take inspiration from nature, where millions of years of evolution led to breakthrough medicines such as penicillin, statins, and taxol. We use computation, synthetic biology, DNA sequencing, and chemistry to mine thousands of fungal genomes, searching for the next treatment for cancer, infectious disease, and other diseases with unmet need.

We believe drug discovery is a problem that requires careful planning and efficient execution, so we focus on upfront data analysis and automated, reproducible biological experiments to maximize the probability of success.

Computational Biologist

As a computational biologist at Hexagon Bio, your job will be to leverage modern computational methods to mine genome data. You will interface with our biology and chemistry teams, helping us use sequencing and synthetic biology to create novel drugs for diseases with unmet need. We are a small team, so we are looking for people who want to take a leadership role, helping us build a successful, next-generation drug company.


Software Engineer, Research

As a software engineer on the research team at Hexagon Bio, your primary responsibility will be to help the research team manage all the data generated by our pipeline, including DNA sequence data, mass spec data, binding assays, etc. You will work with the computational, biology and chemistry teams to create the software infrastructure for a next-generation, data-driven biotech.


Research Associate / Senior Research Associate

The Research Associate (RA) will be introduced to all aspects of Hexagon Bio’s development platforms. You will apply scientific principles and training to facilitate and perform experiments and data analysis with minimal supervision. Knowledge of molecular biology is required and organic chemistry experience is desired. The ideal candidate should be a self-starter who will troubleshoot issues, identify solutions and propose new studies based on findings to further the project needs. You will provide technical support to the senior scientific staff as well as designing and performing experiments for which you will have ownership of the work stream from design and execution of experiments to data analysis and maintenance. Data will be presented to the team and the RA is expected to be a key contributor to the discussion.


Natural Products Chemist

As a natural products chemist at Hexagon Bio, you will join the chemistry team, isolating and characterizing the new drugs being generated by Hexagon Bio’s novel synthetic biology pipeline. The Hexagon chemistry team is a small team of independent scientists, motivated to generate novel medicines.


Assay Biologist

As an assay biologist at Hexagon Bio, your job will be to test small molecules for bioactivities against protein targets of interest. You will interface with our biology and chemistry teams.


Head of Preclinical Development

As Head of Preclinical Development at Hexagon, you will be responsible for the strategy and execution of our preclinical programs. You will direct all aspects of preclinical drug development, from target validation to IND filing.



We are a small team, so we are looking for people who are self-starters, helping us build a successful, next-generation drug company.

Contact Us

Hexagon Bio is located at 1505 Adams Drive, Suite A, Menlo Park, CA 94025

For inquiries, email info@hexagonbio.com