Wed, Sep 22, 2021
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Mon, Mar 21, 2022
Busy Bees: Hexagon Bio Combs Nature’s DNA to Unlock Next-Gen Medicines
Genetic Engineering & Biotechnology News
The company’s platform uses data science, genomics, synthetic biology, and automation to mine microbial genomes for therapeutics to combat human diseases that have evaded traditional approaches
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Fri, Jan 14, 2022
Warring fungi produce new drugs for cancer and infectious disease
Drug Discovery News
Using bioinformatics and machine learning, scientists probe the depths of fungal genomes to find new compounds for undruggable cancers and infections.
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Mon, Jun 04, 2018
This Fungus Could Help Cure Cancer
Bloomberg Businessweek
Scientists are mining the DNA-sequence data from mushrooms and mold to find new drugs.
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Mon, Apr 16, 2018
Hard-to-get fungal natural products found
Chemical & Engineering News
Technique produces compounds made naturally by tough-to-culture fungi or poorly expressed genes.
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Wed, Apr 11, 2018
Hex Technology Cracks Cryptic Codes Identifying Potential Therapeutic Compounds
Technology Networks
Researchers have developed a technology, known as ‘HEx’, that can detect natural products from fungal species – products which are usually extremely difficult to identify. This approach could be used to find natural compounds with therapeutic potential, paving the way to novel antimicrobial drugs.
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Tue, Oct 31, 2017
Scanning Fungal Warscapes for Drug Candidates
Genetic Engineering & Biotechnology News
Hexagon Bio leverages expertise in genomics, synthetic biology, chemistry, and computation to identify small molecules produced by fungi. These molecules, which are of intense interest to drug developers, might otherwise remain hidden.
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Publications & Presentations
Turning the world’s DNA into new medicines
Trends in Biotechnology
J.J. David Ho, Kyle L. Dunbar, Brian Naughton, Colin J.B. Harvey
Read MoreHEx: A heterologous expression platform for the discovery of fungal natural products.
Science Advances
Colin J. B. Harvey, Mancheng Tang, Ulrich Schlecht, Joe Horecka, Curt R. Fischer, Hsiao-Ching Lin, Jian Li, Brian Naughton, James Cherry, Molly Miranda, Yong Fuga Li, Angela M. Chu, James R. Hennessy, Gergana A. Vandova, Diane Inglis, Raeka S. Aiyar, Lars M. Steinmetz, Ronald W. Davis, Marnix H. Medema, Elizabeth Sattely, Chaitan Khosla, Robert P. St. Onge, Yi Tang, and Maureen E. Hillenmeyer.
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